Type 2 Diabetes Mellitus Concerns for Malabsorption of Vitamin B12

Type 2 Diabetes Mellitus Concerns for Malabsorption of Vitamin B12 in People with Lower Diabetes

Metformin is often the first line of medical care for many people with type 2 diabetes, including children. Unlike sulfonylureas, which act on the pancreas, increasing the release of insulin, no metformin is induced to produce more pancreatic insulin.

Unfortunately, prolonged use and high doses of drugs are associated with vitamin B12 deficiency.

Scientists at the Korean Catholic University of Seoul, Korea and the University of South Carolina in the United States, compared metformin therapy in combination to see which combination would be more safe in terms of vitamin B12 than other medicines.

Their study, published in PLoS One October 2014, includes 394 people with type 2 diabetes diagnosed ...
A total of 299 participants were treated with metformin and a sulphonylurea while. The second group of 95 diabetic patients treated with metformin and insulin.

Although the mean levels of B12 were normal, metformin and the sulphonylurea group in both groups a lower protruding ...

The metformin and sulphonylurea group had more cases of vitamin B12 deficiency, with 17.4 percent, compared to second group with 4.2 percent.

From these results it was concluded that type 2 diabetic patients treated with metformin and sulphonylurea should be monitored regularly for vitamin B12 levels.

Sulfonylureas beta cells in the pancreas act causes more insulin release.

Examples of this category of antidiabetic agents include ...

Chloropropamide (Diabinese)
Glimepiride (Amaryl)
Glipizide (Glucotrol, Glucotrol XL)
Glubenclamide (DIABETTA, name GLYNASE PresTab, Micronase)
Tolazamide and

In a vegan diet, claiming to be the best for type 2 diabetes, are B12 sources ...

Nutritional yeast,
B12 and B12 supplements
Grain added,
Meat substitutes and
Non-dairy milk (check the label).

BuzzFeed.com shares 23 recipes with nutritional yeast. Vegan Mac and cheese without cheese. Anyone vegan chicken popcorn? Or enjoy popcorn with food yeast instead of butter. Makes Kale Chips with nutritional yeast a healthy snack.

Some other recipes are BuzzFeed.com veganitas Alfredo pasta, easy vegan pesto, Nachos breakfast, pumpkin zucchini and much more.

Vitamin B12 supplements are also available - alone or in combination with other vitamins and minerals B12. Mayo Clinic recommends USA ...

2.4 mcg B12 for humans over 14 years,
2.6 mcg for pregnant women and
2.8 mcg for breast-feeding women.

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